What Is Bladder Cancer: Overview
Bladder cancer is the fifth most common cancer in the United States, with over 50,000 newly diagnosed cases and over 12,000 deaths annually2
. Bladder cancer is three times more likely to occur in men than in women. The median age at diagnosis is 65 years; bladder cancer is rare in individuals under 402
.
The recurrence rate for bladder cancer is 70 percent; of the approximately 600,000 Americans living with bladder cancer, it is estimated that nearly 400,000 are at risk for recurrence1.
In men, bladder cancer is the fifth most common malignant tumour in Europe and the fourth most common in the USA. In American women it is the 8th most common cancer.
| Total | Male | Female | |
| Bladder Cancer | 449,635 | 330,868 | 118,767 |
| Lung Cancer | 326,895 | 170,608 | 156,287 |
| Prevalence of bladder cancer in the U.S., Source NCI 2002 Fact Sheet | |||
Bladder Cancer Risk Factors
Smoking is the greatest risk factor for bladder cancer, with smokers experiencing twice the risk of nonsmokers for developing the disease. Individuals living in urban areas - especially the American northeast - and those working in the dye, rubber, or leather industries are also at higher risk.
Bladder Cancer Symptoms
The chief initial symptom of bladder cancer is hematuria, or blood in the urine.
Over 90% of bladder cancers in western, industrialized countries are Transitional Cell Carcinomas, so called because these cells have the capability to undergo changes in size from cubical (when the bladder is empty) to flat (when the bladder is full). With such a high rate of recurrence (>70%), it's important to regularly monitor for transitional cell carcinoma recurrence so that it is more likely to be caught early. UroVysion can benefit the physician who is monitoring for recurrence of bladder cancer.
1.Ta, T1 Bladder Cancer: What Can We Learn From EORTC Trials? APM van der Meijden Department of Urology, Bosch Medicentrym, Den Bosch, The Netherlands
2. Memorial Sloan Kettering website; http://www.mskcc.org/
